Keywords

Quick Details

• ProName: (+)-Camptothecin
• CasNo: 7689-03-4
• Molecular Formula: C20H16N2O4
• Appearance: Light Yellow crystalline powder
• Application: It is widely believed that camptotheci...
• DeliveryTime: Within 3 days after receipt of payment
• PackAge: Packed in paper-drums and two plastic-...
• Port: Xiamen
• ProductionCapacity: 100 Kilogram/Month
• Purity: 98%
• Storage: Store in cool & dry place. Keep away f...
• LimitNum: 100 Gram

Superiority

1. With good quality
2. With competitive price
3.100% natural

Product name: Camptothecin
…

Details

1. With good quality
2. With competitive price
3.100% natural

Product name: Camptothecin
CAS No.: 7689-03-4
Formulation: Light Yellow crystalline powder
Purity: 98%

Molecular formula: C20H16N2O4
Molucular weight: 348.36

Usage:
1. Camptothecin and its derivatives are unique in their ability to inhibit DNA Topoisomerase I, by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death.
2. In clinical it is widely believed that camptothecin analogs exhibited remarkable anti-tumour and anti-leukaemia activity. Topoisomerase is a basilic enzyme in the process of DNA replication, it is responsible for the winding / unwinding of the supercoiled DNA composing the chromosomes. If the chromosomes cannot be unwound, transcription of DNA message cannot occur and the protein cannot be synthesized, it ultimately causes cell death.
3.Application of camptothecin in clinic is limited due to serious side effects and poor water-solubility.