Magnolol CAS NO.528-43-8

Botanical Source: Magnolia Officinalis Appearance: light with powder Purity of active compounds: 90%-98% by HPLC Molecular formula: C18H18O2 Molec…

Botanical Source: Magnolia Officinalis Appearance: light with powder Purity of active compounds: 90%-98% by HPLC Molecular formula: C18H18O2 Molecular mass:266.334 Studies of the product: THE protective effect of magnolol, a component of Magnolia officinalis, against hypoxia-induced cell injury in cortical neuron-astrocyte mixed cultures was examined. Exposure of the cells to chemical hypoxia (0.5 mM KCN) produced morphological changes in neurons but not in astrocytes. KCN induced dose- and time-dependent increases in release of LDH and decreases in viable cell number. Treatment with magnolol (10 and 100 μM) significantly reduced the KCN-induced LDH release in a concentration-dependent manner.